Please note that all chapters and page
numbers refer to the assigned textbook, Principles of Human Physiology
by Germann and Stanfield. The assignments from the accompanying CD
are also indicated.
Introductions
You will meet the entire course staff. Email addresses and instructions for making appointments are available from other locations on this 440 - 441 Web site.
Prerequisite Topics from BSCI 230
Review the materials from Chapters 2 through 4, and Chapter 11 before we begin. These pages discuss cell structure, metabolism, membrane transport, and muscle. We assume that you have a thorough understanding of these matters. You must also begin with a review of the Muscle section of the CD. Refer to the questions contained in the CD Exercises section of the Web site to test your knowledge of this subject.
**Before we begin, you must review the concepts found in Chapter 5 (Chemical Messengers), Chapter 6 (Nerve Cells and Electrical Signaling), and Chapter 7 (Synaptic Transmission) to strengthen the understanding you obtained in BSCI 230. You should also work with the Muscle, Nervous System I and II modules of the CD. Do not wait, do it immediately, before the semester begins. NOW! We will briefly review this material in lecture very quickly. Stay tuned.**
Homeostasis:
Chapter 1 (all)
• Consequences of the multicellular condition
• Constant internal environment
• Closed loop, negative feedback control
systems
• Examples
Neurons and Electrical Signaling:
Chapter 6 (all);
*CD,:
Nervous
System Parts 1 & 2
• Membrane potential
• Local, graded potentials
• Action potentials
Synaptic Transmission:
Chapter 7, pages 206 - 214;
*CD:
Nervous
System Part 2
The Autonomic Nervous System:
Chapter 8, pages 223 - 236
Chapter 10 (all)
Chapter 7, pages 214 - 220
• Design of the Mammalian Nervous System
• Central NS
• Peripheral NS
• Afferent
• Efferent
• Somatic
• Autnomic
• Parasympathetic
• Sympathetic
• PNS Pharmacology
• Selected pharmacological agents of interest
Blood
Chapter 13, pages 404 - 411
• Components: characteristics
• Regulation of blood cell production/ differentiation/
destruction
• Hemostasis
Cardiovascular Physiology
*CD:
Cardiovascular
System
• Hemodynamics (Chapter 13; pages
411 - 426)
• Heart (Chapter 12, all)
• Anatomy, cardiac cycle
• Conduction pathways, ECG
• Autorhythmic & contractile cell mechanisms,
E-C coupling
• Innervation & control of cardiac output,
Starling's Law
• 3. Systemic Circulation (Chapter 13,
pages 411 - 440)
• Blood vessel structure & blood flow
• Starling's capillary hypothesis & lymphatic
system
• 4. Cardiovascular Regulation (Chapter
14)
• Systemic vs. pulmonary blood flow,
• Blood pressure regulation
• Cardiovascular disease & exercise physiology
Respiratory Physiology
*CD:
Respiratory
System
• Anatomy of Respiratory System (Chapter
15, pages 470 - 475)
• Mechanics of Breathing (Chapter 15, pages
475 - 494)
• Pulmonary ventilation
• Respiratory volumes & air flow
• Gas Exchange and Transport (Chapter
16; pages 496 - 513)
• Transport of O2, hemoglobin saturation curve, Bohr effect
• Transport of CO2, chloride shift, Haldane effect
• Circulation and Gas Exchange in Tissues
• Regulation of Respiration (Chapter 16,
pages 514 - 526)
• Central regulation
• Chemoreceptors
• Ventilation/ Perfusion regulation
• Respiration role in acid-base balance
• Respiratory disorders & "modifications"
• Diving animals and students
Renal Function
Chapter 17 (all)
Chapter 18, pages 565 - 583
*CD: Renal
System and Fluids and Electrolytes
• Anatomy of the Urinary System
• Structure of the Nephron
• Basic Renal Processes
• Filtration
• Reabsorption
• Secretion
• Specialization within the tubules
• Excretion
• Water Balance
• Osmolarity and the movement of water
• Counter-current exchange mechanism
• ADH
Acid - Base Balance
Chapter 18, pages 583 - 598
• Respiratory mechanisms
• Renal mechanisms
Digestive System
Chapter 19 (all)
• Overview of digestive system function
• Structure of the Gastrointestinal tract
• Enteric nervous system
• Regulation of motility
• Digestion and absorption of nutrient molecules
• Gastrointestinal secretion and motility
• Salivary glands
• Swallowing
• Stomach
• Small intestine
• Large intestine
Mechanisms of Immunity
Chapter 22 (all)
Reproductive System
Chapter 21, pages 670 - 695
• Male reproductive system
• Female reproductive system
Regulation of Metabolism
Chapter 20, pages 649 - 668
• Role of insulin
• Role of glucagon
• Sympathetic action on metabolism
• Other hormonal influences