Macrophages and Host Defense Lab

The Laboratory of Macrophages and Host Defense
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Dr. Ricardo Goncalves

Present Position: Faculty Research Associated - Postdoctoral Fellow

MSc: Veterinary School, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil

PhD: School of Medicine, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil

Research interests:Characterization of monocytes subpopulations during Leishmania spp. infection.

 

Ricardo Gonçalves  Ph.D. (2006)

Present Position: Faculty Research Associated - Postdoctoral Fellow

Previous Position: Coordinator of Veterinary Medicine Course and Director of Veterinary Teaching Hospital - FEAD University – Belo Horizonte, MG, Brazil. Assistant Professor of General Pathology – Federal University of Ouro Preto, Ouro Preto, MG, Brazil

DVM: 1992, School of Veterinary Medicine, Federal University of Uberlandia, MG, Brazil

MSc: 2001, Veterinary School, Federal University of Minas Gerais, MG, Brazil

PhD: 2005, School of Medicine, Federal University of Minas Gerais, MG, Brazil

Research Interests: Characterization of monocytes subpopulations during Leishmania spp. infection. Intracellular IgG traffic during Leishmania spp. infection.  Characterization of subsets of Monocytes and Macrophages during wound healing.

 

  

Publications:

1. LIMA, Wanderson Geraldo, OLIVEIRA, Patrícia Silva, CALIARI, MarceloVidigal, GONCALVES, Ricardo, MICHALICK, Marilene Susan, MELO, Maria Norma, TAFURI, Washington Luiz, TAFURI, Wagner Luiz, Histopathological and immunohistochemical study of type 3 complement receptors (CD11b/CD18) in livers and spleens of asymptomatic and symptomatic dogs naturally infected with Leishmania(Leishmania) chagasi, Veterinary Immunology and Immunopathology, 15;117(1-2):129-36, 2007.

2. XAVIER, Silvio Coura; CHIARELLI, Ingrid Matos; LIMA, Wanderson Geraldo;  GONÇALVES, Ricardo; TAFURI, Wagner Luiz. Canine visceral Leishmaniasis: a remarkable histopathological picture of one asymptomatic animal reported from Belo Horizonte, Minas Gerais, Brazil. Arq. Bras. Med. Vet. Zootec., v.58, n.6, p.994-1000, 2006

3. GONÇALVES, Ricardo; ROCHA-VIEIRA, Etel; MELO, Maria Norma de; GOLLOB, Kenneth John; MOSSER, David M; TAFURI, Wagner Luiz. A sensitive flow cytometric methodology for studying the binding of L. chagasi to canine peritoneal macrophages. Bmc Infectious Diseases, England, v. 5, n. 39, 2005. 

4. TAFURI, Wagner Luiz; SANTOS, Renato Lima dos; ARANTES, Rosa Maria; GONÇALVES, Ricardo; MELO, Maria Norma de; MICHALICK, Marilene Suzan Marques; TAFURI, Washington Luiz. An alternative immunohistochemical method for detecting Leishmania amastigotes in paraffin-embedded canine tissues. Journal of Immunological Methods, England, v. 292, n. 1-2, p. 17-23, 2004. 

5. GONÇALVES, Ricardo; TAFURI, Washington Luiz; MELO, Maria Norma de; RASO, Pedro; TAFURI, Wagner Luiz. Chronic interstitial pneumonitis in dogs naturally infected with Leishmania (Leishmania) chagasi: a histopathological and morphometric study. Revista do Instituto de Medicina Tropical de São Paulo, São Paulo - Brazil, v. 45, n. 3, p. 153-158, 2003. 

Research Summary:

We are interested in the study of Monocytes subsets during Leishmania major infection in mice and in Human beings. Use of these finds to associate with the morbidity and prognosis of Human infected patients.

Recent Work in our Lab has shown a specific traffic of IgG during Leishmania spp. infection. We have been studied these traffic to associate with the severity of the disease.

We are also interested in the study of Monocytes subsets during wound healing.