Effect of inbreeding on H

Selfing: In a population with f (a) = f (A) = 0.5

At Hardy-Weinberg equilibrium, genotypic frequencies are

p2 + 2pq + q2 = 1

AA Aa aa

Parental genotypic frequencies: .25 .50 .25

F1 homozygotes .25 .25

F1 heterozygotes .125 .25 .125

F1 genotypes .375 .25 .375

Conclusion: Frequency of heterozygotes is reduced by 50% with

each generation of selfing.

But there is no loss of allelic diversity: f (a) = f (A) = 0.5