Calculate Junior’s inbreeding coefficients from this pedigree:

AB

CD

Mom

Dad

AC

CC

C = .5

C = .5

C = .5

Sis

Junior (or could

be DD from Dad)

Probability of C from Dad to Sis to Junior = .25

Probability of C from Dad (through Sis) to Junior = .50

Probability of Jr. inheriting CC from Dad = .25 X .50 = .125

Probability of Junior inheriting DD from Dad = .125

F = .125 + .125 = .25 = probability of Jr. being autozygous

31

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