Proteus Summary


  Family Enterobacteriaceae

  Proteus mirabilis
  Proteus vulgaris

  Proteus mirabilis major agent in human infection of urinary tract

  Abundant production of urease

  Urease splits urea (CO(NH2)2) into carbon dioxide (CO2) and ammonia (NH3)
  Ammonia raises the pH of urine and causes the formation of kidney stones (renal stones; renal calculus) which can be extremely painful

  Wound infections, pneumonia, septicemia

  Found in soil, water, sewage, decomposing matter and human intestinal tract

  Hypermotile with cultures demonstrating a swarming phenomena on agar media

  Hydrogen sulfide production

  O, H, K antigens: grouping on basis of these antigens for epidemiologic studies have not been correlative

  Share antigens with the intracellular pathogen Rickettsia

  Treatment: ampicillin and cephalosporins, but resistant strains can develop

   Go to Pathogen List



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