Proteomics



1. In Gibson and Muse read pp. 183-212

2. Read the following three papers:

Aebersold, R. & Mann, M. 2003 Mass spectrometry-based proteomics. Nature 422: 198-207.
 [PDF]

Mayfield, J.A., Fiebig, A., Johnstone, S.E., and Preuss, D. 2001 Gene families from the Arabidopsis thaliana pollen coat proteome. Science 292: 2482-2485. [PDF]


Tyers, M. & Mann, M. 2003 From genomics to proteomics. Nature 422: 193-198. [PDF]

Note the following workshop on this topic:


Exploring the Proteome II - May 2, 2003 Natcher Building 45, Main
Auditorium 8:30 am to 5 pm. Please register (free) in advance to attend
(http://fmp.cit.nih.gov/proteome/).

This symposium features world leaders in proteome research presenting
recent developments and applications in proteomics. Posters from the NIH
community and attendees will be on display in the lobby. The symposium is
organized by the NIH Proteome Interest Group and sponsored by 16 NIH ICs.

Speakers:
Richard M. Caprioli (Vanderbilt University ) Profiling and Imaging of
Proteins in Tissue Sections using Mass Spectrometry as a Discovery Tool in
Biological and Clinical Research

Steven A. Carr (Millennium Pharmaceuticals) Biomarker Discovery by
Proteomics

Donald F. Hunt (University of Virginia) Analysis of Differential Protein
Expression, the Phosphoproteome, Protein-Protein Interactions, and the
Histone Code by Fourier Transform and Ion Trap MS

Carol V. Robinson (Cambridge University) Exploring dynamic protein
interactions using mass spectrometry

Steven P. Gygi (Harvard Medical School) A proteomics approach to
understanding protein ubiquitination

Peter Roepstorff (University of Southern Denmark) Assignment of post
translational modifications is essential in proteomics.

Brian Chait (Rockefeller University) Proteomic Tools for Dissecting
Cellular Function

Rolf Apweiler (European Bioinformatics Institute-Hinxton) Integration
and Standardization: Driving forces in protein informatics

Financed cooperatively by NIMH, NEI, NCI, NIAID, NCRR, NIGMS, NICHD,
NIEHS, NINDS, NHLBI, NIAAA, NIAID, NLM, NIDDK, NIDA, NIAMS, NHGR
Box lunches and refreshments will be provided by Agilent, Amersham
Biosciences, Applied Biosystems, Bruker Daltonics, Eprogen, Shimadzu,
Thermo Finnigan, Waters Corporation and Ciphergen Biosystems.

Individuals with disabilities who need sign language interpreters and/or
reasonable accommodation to participate in this symposium should contact
Ms. Elaine Raab, Laboratory of Neurotoxicology, 301-496-3591,
raabe@codon.nih.gov (or Federal TTY Relay number (1-800-877-8339).
Requests should be made at least 5 days in advance of the event.