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Vacuolar H+-ATPases


V-ATPase Trends Plant Sci 2002 Abstract

The vacuolar-type H+-ATPase acidifies intracellular compartments and is essential for many processes, including cotransport, guard cell movement, development, and tolerance to environmental stress. We have identified at least 26 genes encoding subunits of the V-ATPase in the Arabidopsis thaliana genome, though inconsistent nomenclature of these genes is confusing. The pump consists of subunits A through H of the peripheral V1 complex, and subunit a, c, c" and d of the Vo membrane sector. Most V1 subunits are encoded by a single gene; whereas Vo subunits are encoded by multiple genes found in duplicated segments of the genome. We propose to name these genes VHA-x where x represents the letter code for each subunit. Applying a consistent nomenclature will facilitate efforts to understand how the expression, assembly and activity of this pump are integrated with plant growth, signaling, development, and adaptation.


Contact Dr. Heven Sze:
HJ Patterson Hall * University of Maryland * College Park, MD 20742

Department of Cell Biology & Molecular Genetics | College of Chemical & Life Sciences

University of Maryland