For experimental support for this folding pattern and a discussion of other proposals see:

Song, J., Midson, C., Blachly-Dyson, E., Forte, M., and Colombini, M. 1998. The topology of VDAC as probed by biotin modification. Journal of Biological Chemistry, 273:24406-24413.
 

Please send comments and contributions to Dr. Marco Colombini

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