The Lab
We're an interdisciplinary group working across genomics, stem cell biology, and computational analysis — based in the Bioscience Research Building at the University of Maryland.

Dr. Kan Cao is an aging scientist, inventor, professor, and founder who has spent more than two decades studying why humans age. Her research spans rare premature-aging diseases, Alzheimer's and neurodegeneration, skin and hair aging, and patented applications of methylene blue. A Senior Member of the National Academy of Inventors, she translates complex longevity science into practical insights about how we can live healthier for longer.
kcao@umd.edu · 301-405-3016

Investigating the molecular mechanisms behind LMNA-related congenital muscular dystrophy (L-CMD), a rare skeletal muscle genetic disease.

Investigating impaired mechanotransduction and endothelial dysfunction in Hutchinson-Gilford Progeria Syndrome.

Investigating the molecular and cellular mechanisms underlying neural communication, memory, and cognition, co-mentored by Dr. Losert in Physics and Dr. Cao.

Developing and maintaining the lab's digital platforms and computational infrastructure to support research and communication.

Investigating reactive oxygen species in human cells to understand how external stress influences cellular function.

Investigating the effect of methylene blue on wound healing in human fibroblasts.

Building machine learning and image analysis tools to quantify cellular changes in aging and progeria.

Coordinating laboratory operations by maintaining records, collecting data, and supporting research activities.

Investigating blood-based cellular approaches to physiological resilience and stress response as part of the lab's ARL-supported Cellular Resilience Project, drawing on prior research experience at the NIH, FDA, and in industry and academic settings.
We're always happy to hear from prospective students and postdocs interested in HGPS and aging research.