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Science on Tap

A monthly lecture series at UMD that explores the latest discoveries in science and technology in a relaxed atmosphere with food and drink

"Deciphering Da Vinci’s Code"

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presented by

Norberto González-Juarbe

Norberto González-Juarbe
Associate Professor
Cell Biology & Molecular Genetics
University of Maryland

Monday, October 5, 2026
Doors open at 6 p.m.
Lecture begins at 6:30 p.m.

Ledo Pizza
4509 Knox Rd.
College Park, MD 20740

Food and beverages will be available for purchase at the event. 

Paid parking is available in the attached city garage, which guests can enter on Yale Avenue. Guests may enter the event venue via the Ledo entrance on the corner of Knox Road and Yale Avenue.

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If you have any questions about attending this event, including disability accommodations, please contact Rena Surana-Nirula at rena@umd.edu or 301-405-6563.

Abstract

Cultural heritage objects can retain DNA from their materials, environments and human contact, but analysis is challenged by nondestructive sampling, low biomass and contamination. We developed a minimally invasive workflow combining gentle swabbing, whole-metagenome sequencing, taxonomic profiling and Y-chromosome analysis to examine Renaissance-era artwork and correspondence associated with ancestors of Leonardo da Vinci. We identified diverse microbial and eukaryotic DNA signatures reflecting differences in materials, storage, conservation and handling. Y-chromosome markers from several Leonardo-associated samples suggested assignment within the broader E1b1/E1b1b clade, although controls revealed contributions from modern handling and other sources. These results demonstrate both the potential and limitations of combining metagenomics and human DNA analysis for studies of cultural heritage, provenance, authentication and handling history.

About the SPEAKER

Norberto González-Juarbe is an associate professor in the Department of Cell Biology and Molecular Genetics at the University of Maryland. Originally from Arecibo, Puerto Rico, González-Juarbe is microbiologist and immunologist whose research focuses on host—pathogen interactions, synthetic biology and the development of innovative disease therapies. Beyond his research, he is deeply committed to mentorship, scientific outreach and supporting the next generation of scientists.
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