Introductions

You will meet the entire course staff.  Email addresses and instructions for making appointments are available from other locations on this 440 - 441 Web site.

Prerequisite Topics from BSCI 230

Review the materials from Chapters 2 through 4,  and Chapter 11 before we begin.  These pages discuss cell structure, metabolism, membrane transport, and muscle.  We assume that you have a thorough understanding of these matters.  You must also begin with a review of the Muscle section of the CD.  Refer to the questions contained in the CD Exercises section of the Web site to test your knowledge of this subject.

**Before we begin, you must review the concepts found in Chapter 5 (Chemical Messengers), Chapter 6 (Nerve Cells and Electrical Signaling), and Chapter 7 (Synaptic Transmission) to strengthen the understanding you obtained in BSCI 230.  You should also work with the Muscle, Nervous System I and II modules of the CD.  Do not wait, do it immediately, before the semester begins.  NOW!  We will briefly review this material in lecture very quickly.  Stay tuned.**

Homeostasis:
Chapter 1 (all)
• Consequences of the multicellular condition
• Constant internal environment
• Closed loop, negative feedback control systems
• Examples

Neurons and Electrical Signaling:
Chapter 6 (all);
*CD,: Nervous System Parts  1 & 2
• Membrane potential
• Local, graded potentials
• Action potentials

The Autonomic Nervous System:
Chapter 8, pages 223 - 236
Chapter 10 (all)
Chapter 5, pages 131 - 152
• Design of the Mammalian Nervous System
        • Central NS
        • Peripheral NS
                • Afferent
                • Efferent
                        • Somatic
                        • Autnomic
                                • Parasympathetic
                                • Sympathetic
• PNS Pharmacology
• Selected pharmacological agents of interest

Blood
Chapter 13, pages 404 - 411
• Components: characteristics
• Regulation of blood cell production/ differentiation/ destruction
• Hemostasis

Cardiovascular Physiology
*CD: Cardiovascular System
• Hemodynamics  (Chapter 13; pages 411 - 426)

• Heart (Chapter 12, all)
• Anatomy, cardiac cycle
• Conduction pathways, ECG
• Autorhythmic & contractile cell mechanisms, E-C coupling
• Innervation & control of cardiac output, Starling's Law

• 3. Systemic Circulation (Chapter 13, pages 411 - 440)
• Blood vessel structure & blood flow
• Starling's capillary hypothesis & lymphatic system

• 4. Cardiovascular Regulation (Chapter 14)
• Systemic vs. pulmonary blood flow,
• Blood pressure regulation
• Cardiovascular disease & exercise physiology

Respiratory Physiology
*CD: Respiratory System
• Anatomy of Respiratory System (Chapter 15, pages 470 - 475)

• Mechanics of Breathing (Chapter 15, pages 475 - 494)
• Pulmonary ventilation
• Respiratory volumes & air flow

• Gas Exchange and Transport  (Chapter 16; pages 496 - 513)
        • Transport of O2, hemoglobin saturation curve, Bohr effect
        • Transport of CO2, chloride shift, Haldane effect
        • Circulation and Gas Exchange in Tissues

• Regulation of Respiration (Chapter 16, pages 514 - 526)
        • Central regulation
        • Chemoreceptors
        • Ventilation/ Perfusion regulation
        • Respiration role in acid-base balance

• Respiratory disorders & "modifications"

• Diving animals and students

Renal Function
Chapter 17 (all)
Chapter 18, pages 565 - 583
*CD:  Renal System and Fluids and Electrolytes

• Anatomy of the Urinary System
• Structure of the Nephron
• Basic Renal Processes
        • Filtration
        • Reabsorption
        • Secretion
• Specialization within the tubules
• Excretion
• Water Balance
        • Osmolarity and the movement of water
        • Counter-current exchange mechanism
        • ADH

Acid - Base Balance
Chapter 18, pages 583 - 598

• Respiratory mechanisms
• Renal mechanisms

Digestive System
Chapter 19 (all)

• Overview of digestive system function
• Structure of the Gastrointestinal tract
        • Enteric nervous system
        • Regulation of motility
• Digestion and absorption of nutrient molecules
• Gastrointestinal secretion and motility
        • Salivary glands
        • Swallowing
        • Stomach
        • Small intestine
        • Large intestine

Mechanisms of Immunity
Chapter 22 (all)

Reproductive System
Chapter 21, pages 670 - 695

• Male reproductive system
• Female reproductive system

Regulation of Metabolism
Chapter 20, pages 649 - 668

• Role of insulin
• Role of glucagon
• Sympathetic action on metabolism
• Other hormonal influences